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Addiction risk factors

USP4 · rs6795772

What the study found

Who was studied 300,789 European ancestry problematic alcohol use individuals, 270,120 European ancestry problematic tobacco use individuals, 46,351 European ancestry cannabis use disorder individuals, 30,443 European ancestry opioid use disorder individuals.

The effect Each copy of the C allele shifted the measure 0.014 higher; p = 2 × 10−9.

Where it sits Chromosome 3, band 3p21.31 — in an intron of USP4.

What each result means

C/C Two copies of the version the research linked to Addiction risk factors. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Addiction risk factors. That is a smaller link than two copies.
T/T No copy of the version the research linked to Addiction risk factors. This is the starting point the study compared everyone against.
Source

Questions about rs6795772

What is rs6795772?

rs6795772 is a single position in the genome, in or near the USP4 gene. Published research associates it with addiction risk factors. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6795772 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6795772 come from?

GWAS Catalog, Nature. Mental health 2023, PMID:37250466. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Addiction risk factors (rs6795772). MyGeneLog™. https://www.mygenelog.com/variants/rs6795772

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