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Smoking initiation

near U2SURP · rs13075955

What the study found

Who was studied 3,382,012 European ancestry, East Asian ancestry, Hispanic or Latin American, African ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.00566 higher (95% confidence interval 0.0041-0.0072); p = 1 × 10−12.

How common The T allele had a frequency of about 63% in the people studied.

Where it sits Chromosome 3, band 3q23 — between genes, 10.9 kb from U2SURP.

What each result means

C/C No copy of the version the research linked to Smoking initiation. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Smoking initiation. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Smoking initiation. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs13075955

What is rs13075955?

rs13075955 is a single position in the genome, in or near the near U2SURP gene. Published research associates it with smoking initiation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs13075955 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13075955 come from?

GWAS Catalog, Nature 2022, PMID:36477530. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Smoking initiation (rs13075955). MyGeneLog™. https://www.mygenelog.com/variants/rs13075955

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