0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 88,114 European ancestry individuals.
The effect
Each copy of the C allele carried 1.14 times the odds of Opioid addiction (multi-trait analysis) (95% confidence interval 1.095-1.196); p = 3 × 10−9.
Where it sits Chromosome 6, band 6q25.2 — in an intron of OPRM1.
What each result means
C/CTwo copies of the version the research linked to Opioid addiction (multi-trait analysis). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Opioid addiction (multi-trait analysis). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Opioid addiction (multi-trait analysis). This is the starting point the study compared everyone against.
Scientific reports · 2022 · PMID 36207451 · open access
Questions about rs9478500
What is rs9478500?
rs9478500 is a single position in the genome, in or near the OPRM1 gene. Published research associates it with opioid addiction (multi-trait analysis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does rs9478500 affect how medicines work?
OPRM1 carries pharmacogenomic findings for Opioids. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs9478500 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9478500 come from?
GWAS Catalog, Scientific reports 2022, PMID:36207451. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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