Each page covers one condition properly: what it actually is and what it feels like, what causes it, how common it really is and in whom, and how it's diagnosed — followed by the specific variants with a replicated link to it, and, where the research supports it, how genetics can change the way a medicine behaves.
Written in two registers so one page serves both readers: plain language first, then a clinical detail section with the precise terminology, effect sizes and diagnostic thresholds. Every claim is sourced from freely-available published research and cited on the page, so you can check us — or hand the page to your doctor. 385 conditions so far, growing continuously, and free to reuse with attribution (CC BY 4.0).
25 results in Condition
A 73,265-person GWAS of rosacea symptom severity found 7 loci, split between immune-inflammatory genes and pigmentation genes — a mix that maps onto the two theories long debated about the disease.
Read more → ConditionA 2015 study of every major myositis subtype found that one extended immune haplotype, inherited as a block, accounts for essentially all of the identified genetic risk.
Read more → ConditionThree genome-wide studies spanning a decade, ending in the Million Veteran Program, built a 24-locus genetic map of abdominal aortic aneurysm and found a causal link to diastolic blood pressure.
Read more → ConditionThree GWAS totaling tens of thousands of people, one of them tracing a link to intestinal-pathogen biology, together identified the genetic loci behind the world's most common form of glomerulonephritis.
Read more → ConditionA 2018 meta-analysis of over 200,000 people found 41 risk loci for allergic rhinitis — hay fever — including fine-mapped positions in the HLA region tied to how the immune system recognizes allergens.
Read more →Showing 5 of 25 · page 2 of 2
One diagnosed condition or measurable trait covered properly: what it actually is, what causes it, how common it is, how it is diagnosed, and the specific variants with a replicated link to it — every claim sourced from published research.
No. Every page here is informational, not a diagnosis. A result should be discussed with a doctor or a licensed genetic counselor, never acted on alone.
Because they are not disorders. Height, ABO blood group and a handful of others describe a measurable characteristic with nothing to diagnose — "Trait" says so plainly instead of implying a disease that is not one.
Only after a replicated association in published research, verified against the primary study rather than a gene name or a marketing claim — the same discipline the variant pages themselves follow.