Diagnoses are rising fast; the genetics is real and highly polygenic.
Why this topic Adult diagnoses are rising faster than any other, and so are the questions.
Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.
Counted in Europe PMC, where the title or abstract names both this topic and that rsID. The number is papers, not evidence of a cause.
BDNF
Smoking behavior
13 papers →MTHFR
Folate metabolism (MTHFR A1298C)
4 papers →MTHFR
Folate metabolism (MTHFR C677T)
4 papers →BDNF
Body mass index
2 papers →ADH1B
Alcohol metabolism speed
2 papers →OPRM1
Opioid receptor sensitivity
2 papers →LRRK2
Parkinson's disease
2 papers →BTBD9
Restless legs syndrome
2 papers →FTO
Menarche (age at onset)
2 papers →CACNA1C
Schizophrenia
1 paper →GNPDA2
Obesity
1 paper →KDM4A
Schizophrenia
1 paper →c6orf204
QT interval
1 paper →MAP2K5
Restless legs syndrome
1 paper →DUSP6
ADHD susceptibility (near DUSP6)
1 paper →PAX8
Sleep duration
1 paper →HMGA1
Body mass index
1 paper →MEIS1
Restless legs syndrome
1 paper →SNCA
Parkinson's disease
1 paper →LRP5
Bone mineral density
1 paper →BTBD9
Restless legs syndrome
1 paper →ITGA1
Liver enzyme levels (gamma-glutamyl transferase)
1 paper →APOE
Lewy body disease
1 paper →TAF9BP2
Bipolar disorder or attention deficit hyperactivity disorder
1 paper →BDNP
Menarche (age at onset)
1 paper →FTO
Type 2 diabetes
1 paper →Europe PMC, title and abstract only, searched for “attention deficit hyperactivity disorder”, “ADHD” alongside each published rsID. Full text was not counted: it returns every paper with an rsID buried in a supplementary table. Recounted monthly.
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ADHD and attention. MyGeneLog™. https://www.mygenelog.com/topics/adhd
ADHD and attention is this site's topic page for ADHD genetics — a condition where diagnoses are rising fast and the underlying genetics is real, but spread across many genes rather than concentrated in one.
Yes, but not from one gene. ADHD's genetics is real and highly polygenic, meaning many variants each contribute a small amount rather than a single variant deciding the diagnosis.
Adult ADHD diagnoses are rising faster than diagnoses for almost any other condition, and the questions people ask about the genetics behind that rise are rising just as fast.
Europe PMC is searched for attention deficit hyperactivity disorder or ADHD appearing in a paper's title or abstract alongside a published rsID, recounted every month.