Sensitive

Schizophrenia

CACNA1C · rs1006737

Where this position leads

Condition: Schizophrenia

rs1006737 Condition: Schizophrenia Schizophrenia Condition Topic: Anxiety and worry Anxiety and worry Topic rs1006737 rs1006737 CACNA1C

Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Schizophrenia compared to the general population. (GWAS Catalog, Nat Genet 2013, PMID:23974872)
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Schizophrenia. (GWAS Catalog, Nat Genet 2013, PMID:23974872)
G/G Published research associates this genotype with typical/baseline likelihood of Schizophrenia — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2013, PMID:23974872)

Source: GWAS Catalog, Nat Genet 2013, PMID:23974872

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs1006737

What is rs1006737?

rs1006737 is a single position in the genome, in or near the CACNA1C gene. Published research associates it with schizophrenia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1006737 linked to?

On MyGeneLog this position is linked to Schizophrenia. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs1006737?

Subjects that appear in the title or abstract of the same papers as this rsID include anxiety and worry (3 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs1006737 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1006737 come from?

GWAS Catalog, Nat Genet 2013, PMID:23974872. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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