4 5952248212231Reads by AI crawlersClaude5ChatGPT2Google · Gemini2Perplexity4Meta AI8Microsoft · Copilot2Amazon1Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others31Total59Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.
What the study found
Who was studied 5,001 European ancestry cases, 6,243 European ancestry controls, 8,832 cases, 12,067 controls; replicated in 4,801 European ancestry cases, 4,741 European ancestry controls, 2,612 European and unknown ancestry cases, 15,021 European and unknown ancestry controls, 581 trios.
The effect
Each copy of the A allele carried 1.10 times the odds of Schizophrenia (95% confidence interval 1.08-1.13); p = 5 × 10−12.
How common The A allele had a frequency of about 33% in the people studied.
Where it sits Chromosome 12, band 12p13.33 — in an intron of CACNA1C.
What ClinVar records
ClassificationUncertain risk allele for Post-traumatic stress disorder; no assertion criteria provided (0 of 4 stars, 1 submitter).
ClinVar record 1722519NM_000719.7(CACNA1C):c.477+115699G>A
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
A/ATwo copies of the version the research linked to Schizophrenia. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Schizophrenia. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Schizophrenia. This is the starting point the study compared everyone against.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs1006737
What is rs1006737?
rs1006737 is a single position in the genome, in or near the CACNA1C gene. Published research associates it with schizophrenia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1006737 linked to?
On MyGeneLog this position is linked to Schizophrenia. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs1006737?
Subjects that appear in the title or abstract of the same papers as this rsID include depression and stress (16 papers), learning and focus (8 papers), brain and memory (5 papers), anxiety and worry (3 papers), personality (2 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs1006737 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1006737 come from?
GWAS Catalog, Nat Genet 2013, PMID:23974872. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
4 5952248212231Reads by AI crawlersClaude5ChatGPT2Google · Gemini2Perplexity4Meta AI8Microsoft · Copilot2Amazon1Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others31Total59Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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