Sensitive

Schizophrenia

KDM4A · rs11210892

Where this position leads

Condition: Schizophrenia

rs11210892 Condition: Schizophrenia Schizophrenia Condition rs11210892 rs11210892 KDM4A

What the study found

Who was studied 32,405 European ancestry cases, 42,221 European ancestry controls, 1,235 European ancestry cases and 1,235 European ancestry controls from 1235 parent-offspring trios, 1,836 East Asian ancestry cases, 3,383 East Asian ancestry controls; replicated in 1,513 European ancestry cases, 66,236 European ancestry controls.

The effect Each copy of the A allele carried 1.07 times the odds of Schizophrenia (95% confidence interval 1.05-1.09); p = 3 × 10−10.

How common The A allele had a frequency of about 32% in the people studied.

Where it sits Chromosome 1, band 1p34.2 — between genes, 7.8 kb from PTPRF.

What each result means

A/A Two copies of the version the research linked to Schizophrenia. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Schizophrenia. That is a smaller link than two copies.
G/G No copy of the version the research linked to Schizophrenia. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs11210892

What is rs11210892?

rs11210892 is a single position in the genome, in or near the KDM4A gene. Published research associates it with schizophrenia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11210892 linked to?

On MyGeneLog this position is linked to Schizophrenia. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs11210892?

Subjects that appear in the title or abstract of the same papers as this rsID include adhd and attention (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs11210892 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11210892 come from?

GWAS Catalog, Nature 2014, PMID:25056061. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Schizophrenia (rs11210892). MyGeneLog™. https://www.mygenelog.com/variants/rs11210892

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