Standard

Liver enzyme levels (gamma-glutamyl transferase)

ITGA1 · rs4074793

What the study found

Who was studied Up to 52,350 European ancestry individuals, up to 8,739 Indian Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 5.5 % higher (95% confidence interval 3.30-7.70); p = 3 × 10−10.

How common The G allele had a frequency of about 7% in the people studied.

Where it sits Chromosome 5, band 5q11.2 — in an intron of ITGA1.

What each result means

A/A No copy of the version the research linked to Liver enzyme levels (gamma-glutamyl transferase). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Liver enzyme levels (gamma-glutamyl transferase). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Liver enzyme levels (gamma-glutamyl transferase). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs4074793

What is rs4074793?

rs4074793 is a single position in the genome, in or near the ITGA1 gene. Published research associates it with liver enzyme levels (gamma-glutamyl transferase). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs4074793?

Subjects that appear in the title or abstract of the same papers as this rsID include adhd and attention (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs4074793 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4074793 come from?

GWAS Catalog, Nat Genet 2011, PMID:22001757. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Liver enzyme levels (gamma-glutamyl transferase) (rs4074793). MyGeneLog™. https://www.mygenelog.com/variants/rs4074793

← See all variants