Standard

Body mass index

HMGA1 · rs206936

Where this position leads

Condition: Obesity and Body Weight

rs206936 Condition: Obesity and Body Weight Obesity and Body Weight Condition rs206936 rs206936 HMGA1

What the study found

Who was studied Up to 123,865 European ancestry individuals; replicated in Up to 125,931 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.06 kg/m2 higher (95% confidence interval 0.02-0.10); p = 3 × 10−8.

How common The G allele had a frequency of about 21% in the people studied.

Where it sits Chromosome 6, band 6p21.31 — in an intron of NUDT3.

What each result means

A/A No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs206936

What is rs206936?

rs206936 is a single position in the genome, in or near the HMGA1 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs206936 linked to?

On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs206936?

Subjects that appear in the title or abstract of the same papers as this rsID include adhd and attention (1 papers), blood sugar and insulin (1 papers), risk-taking and impulsivity (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs206936 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs206936 come from?

GWAS Catalog, Nat Genet 2010, PMID:20935630. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs206936). MyGeneLog™. https://www.mygenelog.com/variants/rs206936

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