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Conditions

2

Bitter Taste Perception (TAS2R38) Three coding changes in one bitter receptor gene decide whether compounds like PTC and PROP taste intensely bitter or of almost nothing. It… Chronic Rhinosinusitis and the Bitter Taste Receptor The bitter taste receptor T2R38 is not only on the tongue. It also lines the sinuses, where it detects bacterial signalling molecules and a…

Variants

4

rs10246939 TAS2R38 — Bitter taste perception (TAS2R38 position 296) rs1726866 TAS2R38 — Bitter taste perception (TAS2R38 position 262) rs34210653 ALOX15 — Chronic rhinosinusitis rs713598 TAS2R38 — Bitter taste perception (PTC/PROP tasting)

Drugs

1

Bitter medicines The one entry here that is not about how a drug is handled once it is inside you. It is about whether it gets inside you at all — a medicin…

Topics

6

Smell and taste The one axis you can check on yourself: variants that change the perception rather than the odds. Fertility Genetics has a great deal to say about the timing of reproduction across populations and almost nothing to say to one person trying to conceive. Alcohol and the flush One of the few places where a single variant is visible in the mirror. Exercise and muscle The "sprinter gene" is the most oversold result in consumer genetics. Longevity and ageing The supplement industry's favourite word, and what the data supports. Sleep and insomnia Why some people wake at 5am without an alarm and others cannot.

For classrooms

2

Lesson: how to read a pedigree, and where the textbook rule breaks A free genetics lesson on pedigree analysis. Three clean family trees teach the three inheritance patterns; the fourth is real, and the rul… Lesson: the PTC taste test, and why the textbook version is wrong A ready-to-run genetics lesson built on the PTC taste test — free to use in any school, college or university. Forty minutes, one paper str…

Updates

1

One Gene, Three Answers: What TAS2R38 Decides The same three coding changes decide whether broccoli tastes bitter, play into how your sinuses fight bacteria, and change whether a child …