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23 results for warfarin

All 23 Conditions 1 Variants 11 Drugs 2 Topics 6 News 2 For classrooms 1

Conditions

1
Warfarin Sensitivity and Anticoagulant Dose Variability Warfarin is an anticoagulant whose effective dose varies enormously between people. Common variation in VKORC1 — warfarin's direct target —…

Variants

11
rs104894539 VKORC1 — Warfarin response rs104894540 VKORC1 — Warfarin response rs104894541 VKORC1 — Warfarin response rs1327097914 F9 — Warfarin sensitivity, X-linked rs3794303 CACNA1C — Stable warfarin dose rs4918798 CYP2C9 — Warfarin maintenance dose
Variants 11 →

Drugs

2
Acenocoumarol and phenprocoumon The coumarins much of Europe uses where warfarin is used elsewhere. Same mechanism, same genes, one level of evidence below — because the s… Warfarin A blood thinner whose right dose can differ several times over from one person to the next. Two genes explain more of that difference than …

Topics

6
Where our ancestors came from Ancient DNA and migration: the same positions that differ between populations today. Natural selection Most of what this catalogue tracks is invisible to natural selection — an effect too small, or arriving too late in life, to move the odds … Kidneys Kidney function is reported as a single number, and that number is calculated rather than measured — which is where genetics, and an argume… Bones and fractures Bone density is one of the more heritable things about a body — and the thing that actually matters, whether it breaks, is much harder to p… Cholesterol and blood fats The one axis here where a common variant can move a number a clinic already measures. Lipid levels are among the most heritable ordinary me… Heart and circulation Three different questions wear the same word. Who furs their arteries, who has a heart attack early, and whose heart falls out of rhythm ar…

News

2
Psoriasis and metabolic syndrome share 141 genetic loci, and one candidate gene is warfarin's own VKORC1 Connected to: Psoriasis FDA Approves Updated Warfarin Label Citing CYP2C9 and VKORC1 Genetic Variants Connected to: Warfarin

For classrooms

1
Lesson: when genetic findings don't apply to other populations A free lesson on reading data critically, using this site as the dataset. The class computes the same prediction in five populations and me…