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Conditions

3

Age at Menarche When puberty starts is heritable, polygenic, and moved by years within a century — which tells you how much of it is not genetic. One of th… Obesity and Body Weight A common variant near the FTO gene is linked to a small average increase in body weight and BMI by nudging appetite regulation. Most carrie… Type 2 Diabetes One in nine adults worldwide lives with diabetes, and the great majority of it is type 2. Hundreds of variants each nudge the risk a little…

Variants

10

rs11075990 FTO — Body mass index rs12149832 FTO — Body mass index (SNP x SNP interaction) rs1421085 FTO — Obesity rs1558902 FTO — Obesity rs62033400 FTO — Body mass index rs8050136 FTO — Type 2 diabetes

Topics

24

Smell and taste The one axis you can check on yourself: variants that change the perception rather than the odds. Infection and immunity Whether an infection passes or stays is decided as much by the host as by the microbe — and the host genes that decide it are usually the o… Kidneys Kidney function is reported as a single number, and that number is calculated rather than measured — which is where genetics, and an argume… Fertility Genetics has a great deal to say about the timing of reproduction across populations and almost nothing to say to one person trying to conceive. Bones and fractures Bone density is one of the more heritable things about a body — and the thing that actually matters, whether it breaks, is much harder to p… Alcohol and the flush One of the few places where a single variant is visible in the mirror.