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Running and endurance

Running clubs, first marathons, and a watch telling you your VO2max.

Why this topic Running is the trend of the year, and it comes with a screen full of numbers people now want explained.

What this topic connects to

Running and endurance Variant: rs1815739 rs1815739 Variant Variant: rs762551 rs762551 Variant Variant: rs1799945 rs1799945 Variant Variant: rs9939609 rs9939609 Variant Variant: rs8050136 rs8050136 Variant Variant: +9 more +9 more Variant Running and endurance Running and endurance

Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.

Variants that share a paper with this

Counted in Europe PMC, where the title or abstract names both this topic and that rsID. The number is papers, not evidence of a cause.

rs1815739

ACTN3

Muscle fiber type ("sprinter gene")

35 papers →

rs762551

CYP1A2

Caffeine metabolism

7 papers →

rs1799945

HFE

Iron overload risk (HFE H63D)

6 papers →

rs9939609

FTO

Menarche (age at onset)

6 papers →

rs8050136

FTO

Type 2 diabetes

4 papers →

rs1799971

OPRM1

Opioid receptor sensitivity

2 papers →

rs1800562

HFE

Iron overload risk (hereditary hemochromatosis)

2 papers →

rs1801133

MTHFR

Folate metabolism (MTHFR C677T)

2 papers →

rs429358

APOE

Lewy body disease

2 papers →

rs6025

F5

Blood clotting risk (Factor V Leiden)

2 papers →

rs6265

BDNF

Smoking behavior

2 papers →

rs2014355

ACADS

Metabolite levels

1 paper →

rs4343

ACE

Angiotensin-converting enzyme activity

1 paper →

rs693

APOB

Cholesterol, total

1 paper →

How this was counted

Europe PMC, title and abstract only, searched for “endurance performance”, “endurance athletes”, “marathon runners”, “running economy”, “VO2max”, “aerobic capacity”, “exercise-induced” alongside each published rsID. Full text was not counted: it returns every paper with an rsID buried in a supplementary table. Recounted monthly.

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Running and endurance. MyGeneLog™. https://www.mygenelog.com/topics/running

Questions about Running and endurance

What is Running and endurance?

Running and endurance is this site's topic page for the genetics behind endurance performance — the running-club, first-marathon, VO2max-on-your-watch subject of the moment.

Does genetics explain my VO2max or marathon time?

Only partly. A variant appearing here is co-mentioned with endurance research, not a score of your own aerobic capacity — training, age and the watch's own measurement error all move that number too.

Why is running and endurance a topic on this site now?

Running is the trend of the year, and it arrives with a screen full of numbers — VO2max, running economy, aerobic capacity — that people now want explained.

How does this site decide which variants are linked to running and endurance?

Europe PMC is searched for terms like endurance performance, VO2max, aerobic capacity and marathon runners appearing in a paper's title or abstract alongside a published rsID, recounted every month.