ACADS · rs2014355
Where this position leads
Condition: Blood Metabolite Levels
What the study found
Who was studied 1,029 European ancestry individuals; replicated in 1,202 European ancestry individuals.
The effect Each copy of the T allele shifted the measure 0.218 lower; p = 5 × 10−96.
Where it sits Chromosome 12, band 12q24.31 — in an intron of ACADS.
What ClinVar records
Classification
Benign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 2 submitters), last evaluated 2018-06-14.
ClinVar record 676089 NM_000017.4(ACADS):c.473-116T>C
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
rs2014355 is a single position in the genome, in or near the ACADS gene. Published research associates it with metabolite levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Blood Metabolite Levels. The research behind each link, and its sources, are set out on that condition page.
Subjects that appear in the title or abstract of the same papers as this rsID include exercise and muscle (2 papers), blood sugar and insulin (1 papers), cholesterol and blood fats (1 papers), running and endurance (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nat Genet 2009, PMID:20037589. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Metabolite levels (rs2014355). MyGeneLog™. https://www.mygenelog.com/variants/rs2014355