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682 results for GCK

Conditions

13
Age-Related Macular Degeneration The leading cause of vision loss in older adults in high-income countries. Two genes discovered in 2005 — CFH and ARMS2 — account for most … Birth Weight Birth weight is genetically linked to adult heart disease and diabetes risk — and a large study using both mother and child genotypes found… Cholesterol (LDL, HDL and Total) Nearly a hundred positions here move cholesterol, and each one moves it a little. The two things worth knowing are that very high LDL almos… Gestational Diabetes Mellitus Diabetes that first appears in pregnancy shares most of its known genetics with type 2 diabetes. A 2026 study across British, Finnish and C… Gout Two genes do most of the inherited work here, and both of them are plumbing: one moves urate out through the kidney, the other out through … Height The textbook polygenic trait, with the number usually left out: 12,111 positions, none of which means anything alone. It is also the cleare…
Conditions 13 →

Variants

662
rs1000236360 GCK — Hyperinsulinemic hypoglycemia, familial, 3 rs1007314573 GCK — Maturity-onset diabetes of the young rs1010302320 GCK — Maturity-onset diabetes of the young type 2 rs10259649 GCK — Prediabetes rs1036483919 GCK — Monogenic diabetes rs104894005 GCK — Maturity-onset diabetes of the young type 2
Variants 662 →

Topics

5
Where our ancestors came from Ancient DNA and migration: the same positions that differ between populations today. Natural selection Most of what this catalogue tracks is invisible to natural selection — an effect too small, or arriving too late in life, to move the odds … Exercise and muscle The "sprinter gene" is the most oversold result in consumer genetics. Cholesterol and blood fats The one axis here where a common variant can move a number a clinic already measures. Lipid levels are among the most heritable ordinary me… Blood sugar and insulin The most-studied common disease there is, and the one where the gap between what genetics found and what changes an outcome is widest. Hund…

News

1
Multi-ancestry, trans-generational GWAS meta-analysis of gestational diabetes and glycaemic traits during pregnancy reveals limited evidence of pregnancy-specific genetic effects Connected to: Gestational Diabetes Mellitus (+6 more)

Updates

1
World Diabetes Day: MODY, the Diabetes That Runs in Families Through One Gene Most diabetes is type 1 or type 2. A small share comes from a single gene, passes straight from parent to child, and is often mistaken for …