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Risk-taking and impulsivity

Trading, betting, and every "should I?" at 2am. Over a million people were studied: 99 positions turned up, 46 of them shared with risky behaviour in driving, drinking, smoking or sex — one disposition showing through in several places at once. And none of the genes previously famous for this survived.

Why this topic Crypto, prediction markets and day trading made "impulse" a word people apply to themselves — and the 2019 analysis found no enrichment at all among the genes twenty years of smaller studies had named. The effect that is real is spread across hundreds of positions and says nothing about any one person.

Source: Karlsson Linnér et al., Nature Genetics 2019 — risk tolerance and risky behaviours in over 1 million individuals

In the news

2026-09-01 · Northwestern Mutual (Harris Poll, n=4,375 U.S. adults)

When New Investment Trends Emerge, Gen Z Is Most Likely Generation to Be First In

37% of Gen Z respondents said they prefer calculated risk for higher returns, versus 14% of Boomers+ — a survey finding, not a genetic one, but the same generational risk-tolerance split this topic's underlying genetics describes.

What this topic connects to

Risk-taking and impulsivity Variant: rs6265 rs6265 Variant Variant: rs1799971 rs1799971 Variant Variant: rs9939609 rs9939609 Variant Variant: rs11030104 rs11030104 Variant Variant: rs429358 rs429358 Variant Variant: +9 more +9 more Variant Risk-taking and impulsivity Risk-taking and impulsivity

Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.

Named by the study itself

These three are not co-mentions. They appear in the study's own list of associated positions — and they are the only three of its loci this site holds. What they are here for is worth noticing: alcohol metabolism, ADHD and smoking. The same disposition, showing up under three different headings.

rs1229984

ADH1B

Alcohol metabolism speed

rs3001723

PTPRF

ADHD susceptibility (PTPRF)

rs6265

BDNF

Smoking behavior

Variants that share a paper with this

Counted in Europe PMC, where the title or abstract names both this topic and that rsID. The number is papers, not evidence of a cause.

rs6265

BDNF

Smoking behavior

9 papers →

rs1799971

OPRM1

Opioid receptor sensitivity

3 papers →

rs9939609

FTO

Menarche (age at onset)

3 papers →

rs11030104

BDNF

Body mass index

2 papers →

rs429358

APOE

Lewy body disease

2 papers →

rs7103411

BDNP

Menarche (age at onset)

2 papers →

rs10146997

NRXN3

Waist circumference

1 paper →

rs10938397

GNPDA2

Obesity

1 paper →

rs10994336

ANK3

Bipolar disorder

1 paper →

rs1421085

FTO

Obesity

1 paper →

rs1801131

MTHFR

Folate metabolism (MTHFR A1298C)

1 paper →

rs1801133

MTHFR

Folate metabolism (MTHFR C677T)

1 paper →

rs206936

HMGA1

Body mass index

1 paper →

rs3829251

NADSYN1

Vitamin D levels

1 paper →

How this was counted

Europe PMC, title and abstract only, searched for “risk tolerance”, “risk taking”, “impulsivity”, “sensation seeking”, “delay discounting” alongside each published rsID. Full text was not counted: it returns every paper with an rsID buried in a supplementary table. Recounted monthly.

Quoting this page

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Risk-taking and impulsivity. MyGeneLog™. https://www.mygenelog.com/topics/risk-taking

Questions about Risk-taking and impulsivity

What is Risk-taking and impulsivity?

Risk-taking and impulsivity is this site's topic page for the genetics behind trading, betting and everyday impulsive decisions — grounded in the largest study of the trait, which found the effect spread across many positions rather than concentrated in a few famous genes.

Does genetics predict whether someone is a risk-taker?

No single gene does. Over a million people were studied and 99 positions turned up, but none work alone, and the genes previously famous for explaining risk-taking did not survive the analysis. What is real is spread thin across hundreds of positions.

Why does risk-taking and impulsivity matter as a topic this year?

Crypto, prediction markets and day trading made "impulse" a word people now apply to themselves, right as the largest study of it found no enrichment at all among the genes twenty years of smaller studies had named.

What are the three "confirmed" variants on the risk-taking and impulsivity page?

They are not co-mentions like the rest of the list — they are the only three of the study's own associated positions this site happens to publish. What they are tied to is telling: alcohol metabolism, ADHD and smoking, one disposition under three different headings.