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Conditions

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MTHFR Variants and Folate Metabolism Two very common MTHFR variants modestly change how efficiently one folate-processing enzyme works. They are heavily over-claimed online; he…

Variants

2

rs1801131 MTHFR — Folate metabolism (MTHFR A1298C) rs1801133 MTHFR — Folate metabolism (MTHFR C677T)

Topics

22

Smell and taste The one axis you can check on yourself: variants that change the perception rather than the odds. Infection and immunity Whether an infection passes or stays is decided as much by the host as by the microbe — and the host genes that decide it are usually the o… Kidneys Kidney function is reported as a single number, and that number is calculated rather than measured — which is where genetics, and an argume… Liver The organ people only think about when a blood test comes back odd. Two of its commonest numbers are partly inherited, which is why a raise… Fertility Genetics has a great deal to say about the timing of reproduction across populations and almost nothing to say to one person trying to conceive. Bones and fractures Bone density is one of the more heritable things about a body — and the thing that actually matters, whether it breaks, is much harder to p…

Updates

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Research roundup — September 2026 11 new papers published this month on variants MyGeneLog covers. MTHFR Explained: What rs1801133 Actually Means MTHFR shows up in a lot of alarming corners of the internet. Here is what the actual research says.