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Who was studied 8,809 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.112 lower (95% confidence interval 0.083-0.141); p = 3 × 10−13.
Where it sits Chromosome 10, band 10q23.33 — in an intron of CYP2C9.
What each result means
A/ATwo copies of the version the research linked to X-17654 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to X-17654 levels. That is a smaller link than two copies.
T/TNo copy of the version the research linked to X-17654 levels. This is the starting point the study compared everyone against.
rs1934969 is a single position in the genome, in or near the CYP2C9 gene. Published research associates it with x-17654 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does rs1934969 affect how medicines work?
CYP2C9 carries pharmacogenomic findings for Acenocoumarol and phenprocoumon, NSAIDs, Phenytoin and fosphenytoin, Siponimod, Statins, Sulfonylureas, Warfarin. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs1934969 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1934969 come from?
GWAS Catalog, Metabolites 2022, PMID:35050183. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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