The same pharmacogenomics that sits on our condition pages, read from the other end. People rarely arrive asking about SLCO1B1 — they arrive having been prescribed a statin. Each page below collects what published guidelines say about one drug, names the genes involved, and links to the variants your own file would contain.
Supplements — kept apart, with the evidence stated on each →
None of this is dosing guidance. Where a clinical guideline exists it is written for prescribers, and the pages say so. Nothing here is a reason to start, stop or change a medication.
The painkillers people reach for without thinking, and the only reason genotype comes into it is that the harms are dose-dependent and the dose in your blood is not the dose on the packet.
CYP2C9
See what the research says → AnalgesicProdrugs, which is what makes them different from the other opioids: the enzyme does not clear them, it switches them on. Too little and there is no pain relief; too much and there is far more drug than intended.
CYP2D6
See what the research says → AnalgesicOne of the most studied genes in all of pharmacogenomics sits here — and the guideline that reviewed it concluded that no dosing recommendation can be made. That conclusion is the finding.
OPRM1 · OPRM1 (upstream locus)
See what the research says →The same pharmacogenomics already published on our condition pages, read from the drug side instead: what published guidelines say about one medicine, which genes are involved, and the variants your own file would contain.
No. Where a clinical guideline exists it is written for prescribers, and nothing here is a reason to start, stop or change a medication — that belongs with the clinician or pharmacist managing treatment.
Because almost nothing sold as a supplement has a prescribing guideline behind it the way a drug does, and listing the two together would lend the second the authority of the first.
By gene symbol as a whole word, gathered from the pgx_notes already published on the condition pages that discuss each drug — not a second, separate copy of that information.