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Metabolite levels

FADS1 · rs174547

Where this position leads

Condition: Blood Metabolite Levels

Supplement: Omega-3 fatty acids (fish oil)

rs174547 Condition: Blood Metabolite Levels Blood Metabolite Levels Condition Supplement: Omega-3 fatty acids (fish oil) Omega-3 fatty acids (fish oil) Supplement Topic: Cholesterol and blood fats Cholesterol and blood fats Topic Topic: Blood sugar and insulin Blood sugar and insulin Topic Topic: Heart and circulation Heart and circulation Topic rs174547 rs174547 FADS1

Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.

What the study found

Who was studied 1,029 European ancestry individuals; replicated in 1,202 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.151 higher; p = 7 × 10−179.

Where it sits Chromosome 11, band 11q12.2 — in an intron of FADS2.

What each result means

C/C No copy of the version the research linked to Metabolite levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Metabolite levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Metabolite levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs174547

What is rs174547?

rs174547 is a single position in the genome, in or near the FADS1 gene. Published research associates it with metabolite levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs174547 linked to?

On MyGeneLog this position is linked to Blood Metabolite Levels. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs174547?

Subjects that appear in the title or abstract of the same papers as this rsID include cholesterol and blood fats (6 papers), heart and circulation (5 papers), blood sugar and insulin (5 papers), liver (1 papers), alcohol and the flush (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs174547 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs174547 come from?

GWAS Catalog, Nat Genet 2009, PMID:20037589. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Metabolite levels (rs174547). MyGeneLog™. https://www.mygenelog.com/variants/rs174547

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