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Who was studied 36,615 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0789 SD units higher (95% confidence interval 0.061-0.097); p = 5 × 10−18.
How common The G allele had a frequency of about 19% in the people studied.
Where it sits Chromosome 6, band 6p21.33 — in an intron of HLA-B.
What each result means
G/GTwo copies of the version the research linked to Immature platelet fraction. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to Immature platelet fraction. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Immature platelet fraction. This is the starting point the study compared everyone against.
Nature communications · 2023 · PMID 37596262 · open access
Questions about rs9266265
What is rs9266265?
rs9266265 is a single position in the genome, in or near the HLA-B gene. Published research associates it with immature platelet fraction. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does rs9266265 affect how medicines work?
HLA-B carries pharmacogenomic findings for Abacavir, Allopurinol, Carbamazepine and oxcarbazepine. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs9266265 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9266265 come from?
GWAS Catalog, Nature communications 2023, PMID:37596262. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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