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Who was studied 453,169 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0201 lower (95% confidence interval 0.016-0.024); p = 1 × 10−21.
How common The A allele had a frequency of about 87% in the people studied.
Where it sits Chromosome 6, band 6p21.33 — between genes, 6 kb from HLA-B.
What each result means
A/ATwo copies of the version the research linked to Body size at age 10. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Body size at age 10. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Body size at age 10. This is the starting point the study compared everyone against.
BMJ (Clinical research ed.) · 2020 · PMID 32376654 · open access
Questions about rs9265968
What is rs9265968?
rs9265968 is a single position in the genome, in or near the HLA-B gene. Published research associates it with body size at age 10. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does rs9265968 affect how medicines work?
HLA-B carries pharmacogenomic findings for Abacavir, Allopurinol, Carbamazepine and oxcarbazepine. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs9265968 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9265968 come from?
GWAS Catalog, BMJ (Clinical research ed.) 2020, PMID:32376654. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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Body size at age 10 (rs9265968). MyGeneLog™. https://www.mygenelog.com/variants/rs9265968