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Body mass (lean)

TRHR · rs7832552

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 973 European ancestry individuals; replicated in 1,488 European ancestry individuals, 1,972 European ancestry individuals from 593 families, 2,955 Chinese ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.1 kg higher (95% confidence interval 0.04-0.16); p = 4 × 10⁻¹⁰.

How common The T allele had a frequency of about 32% in the people studied.

Where it sits Chromosome 8, band 8q23.1 — in an intron of TRHR.

What each result means

C/C No copy of the version the research linked to Body mass (lean). This is the starting point the study compared everyone against.

C/T One copy of the version the research linked to Body mass (lean). That is a smaller link than two copies.

T/T Two copies of the version the research linked to Body mass (lean). That is the strongest link of the three results. A link in a study is not a diagnosis.

Source

Genome-wide association and replication studies identified TRHR as an important gene for lean body mass

Liu XG, Tan LJ, Lei SF, Liu YJ, Shen H, Wang L, Yan H, Guo YF, Xiong DH, Chen XD, Pan F, Yang TL

and 9 more — show all

Zhang YP, Guo Y, Tang NL, Zhu XZ, Deng HY, Levy S, Recker RR, Papasian CJ, Deng HW

American journal of human genetics · 2009 · PMID 19268274

What people read about alongside this

Exercise and muscle2 Sport and performance2

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs7832552

What is rs7832552?

rs7832552 is a single position in the genome, in or near the TRHR gene. Published research associates it with body mass (lean). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs7832552?

Subjects that appear in the title or abstract of the same papers as this rsID include exercise and muscle (2 papers), sport and performance (2 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs7832552 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7832552 come from?

GWAS Catalog, Am J Hum Genet 2009, PMID:19268274. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass (lean) (rs7832552). MyGeneLog™. https://www.mygenelog.com/variants/rs7832552

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