Standard

Coffee consumption

AHR · rs6968865

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 5,840 European ancestry individuals, 771 Sorbian (founder/genetic isolate) individuals; replicated in 4,050 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.26 cups per day higher (95% confidence interval 0.15-0.36); p = 2 × 10⁻¹¹.

How common The T allele had a frequency of about 59% in the people studied.

Where it sits Chromosome 7, band 7p21.1 — in an intron of AHR.

What each result means

A/A No copy of the version the research linked to Coffee consumption. This is the starting point the study compared everyone against.

A/T One copy of the version the research linked to Coffee consumption. That is a smaller link than two copies.

T/T Two copies of the version the research linked to Coffee consumption. That is the strongest link of the three results. A link in a study is not a diagnosis.

Source

Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption

Sulem P, Gudbjartsson DF, Geller F, Prokopenko I, Feenstra B, Aben KK, Franke B, den Heijer M, Kovacs P, Stumvoll M, Mägi R, Yanek LR

and 18 more — show all

Becker LC, Boyd HA, Stacey SN, Walters GB, Jonasdottir A, Thorleifsson G, Holm H, Gudjonsson SA, Rafnar T, Björnsdottir G, Becker DM, Melbye M, Kong A, Tönjes A, Thorgeirsson T, Thorsteinsdottir U, Kiemeney LA, Stefansson K

Human molecular genetics · 2011 · PMID 21357676

What people read about alongside this

Caffeine and energy drinks4 Blood sugar and insulin1 Heart and circulation1

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

From our blog

Two identical cups of coffee, one calm and one trembling

Why One Cup of Coffee Wrecks You and Not Your Friend: Meet CYP1A2

One friend sleeps fine after a late americano; another shakes after a single cup. There is a real gene behind …

Questions about rs6968865

What is rs6968865?

rs6968865 is a single position in the genome, in or near the AHR gene. Published research associates it with coffee consumption. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs6968865?

Subjects that appear in the title or abstract of the same papers as this rsID include caffeine and energy drinks (4 papers), blood sugar and insulin (1 papers), heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs6968865 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6968865 come from?

GWAS Catalog, Hum Mol Genet 2011, PMID:21357676. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Coffee consumption (rs6968865). MyGeneLog™. https://www.mygenelog.com/variants/rs6968865

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