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Who was studied 403,943 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0274 higher (95% confidence interval 0.023-0.031); p = 2 × 10−40.
How common The A allele had a frequency of about 68% in the people studied.
Where it sits Chromosome 6, band 6p21.33 — between genes, 21.4 kb from HLA-B.
What each result means
A/ATwo copies of the version the research linked to HDL cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to HDL cholesterol levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to HDL cholesterol levels. This is the starting point the study compared everyone against.
PLoS medicine · 2020 · PMID 32203549 · open access
Questions about rs6902116
What is rs6902116?
rs6902116 is a single position in the genome, in or near the HLA-B gene. Published research associates it with hdl cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does rs6902116 affect how medicines work?
HLA-B carries pharmacogenomic findings for Abacavir, Allopurinol, Carbamazepine and oxcarbazepine. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs6902116 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6902116 come from?
GWAS Catalog, PLoS medicine 2020, PMID:32203549. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 241122216Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others16Total24Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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