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Who was studied 98,316 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.00139 lower (95% confidence interval 0.00092-0.00186); p = 3 × 10−9.
How common The T allele had a frequency of about 17% in the people studied.
Where it sits Chromosome 4, band 4q22.1 — in an intron of ABCG2.
What each result means
A/ANo copy of the version the research linked to Leucine levels. This is the starting point the study compared everyone against.
A/TOne copy of the version the research linked to Leucine levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Leucine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Ophthalmology science · 2024 · PMID 39091897 · open access
Questions about rs6811890
What is rs6811890?
rs6811890 is a single position in the genome, in or near the ABCG2 gene. Published research associates it with leucine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6811890 linked to?
On MyGeneLog this position is linked to Age-Related Macular Degeneration. The research behind each link, and its sources, are set out on that condition page.
Does rs6811890 affect how medicines work?
ABCG2 carries pharmacogenomic findings for Statins. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs6811890 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6811890 come from?
GWAS Catalog, Ophthalmology science 2024, PMID:39091897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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