G/GPublished research associates this genotype with typical/baseline likelihood of Bilirubin levels — no copies of the reported risk allele.
G/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Bilirubin levels.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Bilirubin levels compared to the general population.
rs6742078 is a single position in the genome, in or near the UGT1A1 gene. Published research associates it with bilirubin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does rs6742078 affect how medicines work?
UGT1A1 carries pharmacogenomic findings for Atazanavir, Irinotecan. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs6742078 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6742078 come from?
GWAS Catalog, Hum Mol Genet 2009, PMID:19414484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.