LDLR · rs6511720
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 12,126 European ancestry individuals, 1,538 individuals.
The effect Each copy of the T allele shifted the measure 0.045 lower (95% confidence interval 0.031-0.059); p = 3 × 10−11.
How common The T allele had a frequency of about 10% in the people studied.
Where it sits Chromosome 19, band 19p13.2 — in an intron of LDLR.
What ClinVar records
Classification
Benign for Hypercholesterolemia, familial, 1, Familial hypercholesterolemia; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 3 submitters), last evaluated 2025-12-08.
ClinVar record 250988 NM_000527.5(LDLR):c.67+2015G>T
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
rs6511720 is a single position in the genome, in or near the LDLR gene. Published research associates it with lipoprotein-associated phospholipase a2 activity and mass. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Subjects that appear in the title or abstract of the same papers as this rsID include cholesterol and blood fats (8 papers), heart and circulation (6 papers), blood sugar and insulin (2 papers), infection and immunity (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Eur Heart J 2011, PMID:22003152. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Lipoprotein-associated phospholipase A2 activity and mass (rs6511720). MyGeneLog™. https://www.mygenelog.com/variants/rs6511720