Stromal cell-derived factor 2 level in Chronic kidney disease with hypertension and no diabetes (15333_11)
HLA-B · rs62396274
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The effect
Each copy of the A allele shifted the measure 1.6 higher (95% confidence interval 1.25-1.95); p = 5 × 10−18.
How common The A allele had a frequency of about 3% in the people studied.
Where it sits Chromosome 6, band 6p21.33 — in an intron of HLA-B.
What each result means
A/ATwo copies of the version the research linked to Stromal cell-derived factor 2 level in Chronic kidney disease with hypertension and no diabetes (15333_11). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Stromal cell-derived factor 2 level in Chronic kidney disease with hypertension and no diabetes (15333_11). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Stromal cell-derived factor 2 level in Chronic kidney disease with hypertension and no diabetes (15333_11). This is the starting point the study compared everyone against.
rs62396274 is a single position in the genome, in or near the HLA-B gene. Published research associates it with stromal cell-derived factor 2 level in chronic kidney disease with hypertension and no diabetes (15333_11). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does rs62396274 affect how medicines work?
HLA-B carries pharmacogenomic findings for Abacavir, Allopurinol, Carbamazepine and oxcarbazepine. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs62396274 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs62396274 come from?
GWAS Catalog, Kidney international 2022, PMID:35870639. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 9126Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others6Total9Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
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Stromal cell-derived factor 2 level in Chronic kidney disease with hypertension and no diabetes (15333_11) (rs62396274). MyGeneLog™. https://www.mygenelog.com/variants/rs62396274