A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Systemic lupus erythematosus compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Systemic lupus erythematosus.
G/GPublished research associates this genotype with typical/baseline likelihood of Systemic lupus erythematosus — no copies of the reported risk allele.
Annals of the rheumatic diseases · 2021 · PMID 33272962 · open access
Questions about rs5945199
What is rs5945199?
rs5945199 is a single position in the genome, in or near the G6PD gene. Published research associates it with systemic lupus erythematosus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs5945199 linked to?
On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.
Does rs5945199 affect how medicines work?
G6PD carries pharmacogenomic findings for Dapsone, nitrofurantoin and other oxidising drugs, Primaquine and tafenoquine, Rasburicase. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs5945199 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs5945199 come from?
GWAS Catalog, Ann Rheum Dis 2020, PMID:33272962. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.