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Soluble E-selectin levels

ABO · rs579459

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 685 European ancestry individuals with type 1 diabetes; replicated in 477 European ancestry individuals.

The effect The reported allele is C; the catalogue records no effect size ; p = 1 × 10⁻²⁹.

How common The C allele had a frequency of about 20% in the people studied.

Where it sits Chromosome 9, band 9q34.2 — between genes, 2.7 kb from ABO.

What each result means

C/C Two copies of the version the research linked to Soluble E-selectin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.

C/T One copy of the version the research linked to Soluble E-selectin levels. That is a smaller link than two copies.

T/T No copy of the version the research linked to Soluble E-selectin levels. This is the starting point the study compared everyone against.

Source

Genome-wide association identifies the ABO blood group as a major locus associated with serum levels of soluble E-selectin

Paterson AD, Lopes-Virella MF, Waggott D, Boright AP, Hosseini SM, Carter RE, Shen E, Mirea L, Bharaj B, Sun L, Bull SB

Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group

Arteriosclerosis, thrombosis, and vascular biology · 2009 · PMID 19729612

What people read about alongside this

Heart and circulation10 Sleep and insomnia3 Blood sugar and insulin1 Cholesterol and blood fats1 Liver1

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs579459

What is rs579459?

rs579459 is a single position in the genome, in or near the ABO gene. Published research associates it with soluble e-selectin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs579459?

Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (10 papers), sleep and insomnia (3 papers), blood sugar and insulin (1 papers), cholesterol and blood fats (1 papers), liver (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs579459 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs579459 come from?

GWAS Catalog, Arterioscler Thromb Vasc Biol 2009, PMID:19729612. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Soluble E-selectin levels (rs579459). MyGeneLog™. https://www.mygenelog.com/variants/rs579459

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