alpha-2-macroglobulin receptor-associated protein levels
HLA-B · rs41559422
0 1811214Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others14Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 10,708 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 1.81 higher (95% confidence interval 1.75-1.87).
How common The A allele had a frequency of about 3% in the people studied.
Where it sits Chromosome 6, band 6p21.33 — in an intron of HLA-B.
What each result means
A/ATwo copies of the version the research linked to alpha-2-macroglobulin receptor-associated protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to alpha-2-macroglobulin receptor-associated protein levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to alpha-2-macroglobulin receptor-associated protein levels. This is the starting point the study compared everyone against.
rs41559422 is a single position in the genome, in or near the HLA-B gene. Published research associates it with alpha-2-macroglobulin receptor-associated protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does rs41559422 affect how medicines work?
HLA-B carries pharmacogenomic findings for Abacavir, Allopurinol, Carbamazepine and oxcarbazepine. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs41559422 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs41559422 come from?
GWAS Catalog, Science (New York, N.Y.) 2021, PMID:34648354. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1811214Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others14Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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alpha-2-macroglobulin receptor-associated protein levels (rs41559422). MyGeneLog™. https://www.mygenelog.com/variants/rs41559422