0 131129Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others9Total13Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 1,296 European ancestry cases, 482,717 European ancestry controls, 303 East Asian ancestry cases, 175,599 East Asian ancestry controls.
The effect
Each copy of the A allele shifted the measure 0.709 higher (95% confidence interval 0.58-0.84); p = 6 × 10−28.
Where it sits Chromosome 6, band 6p21.33 — in a non-coding transcript of HLA-B.
What each result means
A/ATwo copies of the version the research linked to Sjögren's syndrome. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Sjögren's syndrome. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Sjögren's syndrome. This is the starting point the study compared everyone against.
rs2523571 is a single position in the genome, in or near the HLA-B gene. Published research associates it with sjögren's syndrome. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2523571 linked to?
On MyGeneLog this position is linked to Sjögren's Syndrome. The research behind each link, and its sources, are set out on that condition page.
Does rs2523571 affect how medicines work?
HLA-B carries pharmacogenomic findings for Abacavir, Allopurinol, Carbamazepine and oxcarbazepine. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs2523571 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2523571 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 131129Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others9Total13Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.