Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio)
ARID3B · rs2470893
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 5,323 European ancestry individuals; replicated in 824 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 7.85 Z-score higher (95% confidence interval -); p = 4 × 10−15.
How common The T allele had a frequency of about 33% in the people studied.
Where it sits Chromosome 15, band 15q24.1 — between genes, 1.6 kb from CYP1A1.
What each result means
C/CNo copy of the version the research linked to Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio). That is the strongest link of the three results. A link in a study is not a diagnosis.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs2470893
What is rs2470893?
rs2470893 is a single position in the genome, in or near the ARID3B gene. Published research associates it with caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What do people read about alongside rs2470893?
Subjects that appear in the title or abstract of the same papers as this rsID include caffeine and energy drinks (9 papers), blood sugar and insulin (3 papers), heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs2470893 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2470893 come from?
GWAS Catalog, Hum Mol Genet 2016, PMID:27702941. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
6 523218222230Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity1Meta AI8Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others30Total52Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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