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Interleukin-18 levels

BCO2 · rs1834481

What the study found

Who was studied 1,523 European ancestry female individuals; replicated in 435 European ancestry female individuals.

The effect The reported allele is G; the catalogue records no effect size ; p = 1 × 10−8.

How common The G allele had a frequency of about 24% in the people studied.

Where it sits Chromosome 11, band 11q23.1 — in an intron of IL18.

What each result means

C/C No copy of the version the research linked to Interleukin-18 levels. This is the starting point the study compared everyone against.
C/G One copy of the version the research linked to Interleukin-18 levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Interleukin-18 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs1834481

What is rs1834481?

rs1834481 is a single position in the genome, in or near the BCO2 gene. Published research associates it with interleukin-18 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs1834481?

Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (2 papers), depression and stress (1 papers), heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs1834481 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1834481 come from?

GWAS Catalog, Arterioscler Thromb Vasc Biol 2010, PMID:20150558. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Interleukin-18 levels (rs1834481). MyGeneLog™. https://www.mygenelog.com/variants/rs1834481

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