Free Cholesterol to Cholesteryl Esters in Small HDL ratio
CLMN · rs147638906
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Who was studied 98,316 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.157 higher (95% confidence interval 0.1-0.21); p = 6 × 10−9.
How common The G allele had a frequency of about 1% in the people studied.
Where it sits Chromosome 14, band 14q32.13 — in an intron of CLMN.
What each result means
C/CNo copy of the version the research linked to Free Cholesterol to Cholesteryl Esters in Small HDL ratio. This is the starting point the study compared everyone against.
C/GOne copy of the version the research linked to Free Cholesterol to Cholesteryl Esters in Small HDL ratio. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Free Cholesterol to Cholesteryl Esters in Small HDL ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Ophthalmology science · 2024 · PMID 39091897 · open access
Questions about rs147638906
What is rs147638906?
rs147638906 is a single position in the genome, in or near the CLMN gene. Published research associates it with free cholesterol to cholesteryl esters in small hdl ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs147638906 linked to?
On MyGeneLog this position is linked to Age-Related Macular Degeneration. The research behind each link, and its sources, are set out on that condition page.
Does rs147638906 affect how medicines work?
CLMN carries pharmacogenomic findings for Statins. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs147638906 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs147638906 come from?
GWAS Catalog, Ophthalmology science 2024, PMID:39091897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 2811122219Reads by AI crawlersClaude1ChatGPT1Google · Gemini1Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others19Total28Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Free Cholesterol to Cholesteryl Esters in Small HDL ratio (rs147638906). MyGeneLog™. https://www.mygenelog.com/variants/rs147638906