0 2711123316Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)3ByteDance (Doubao)3Others16Total27Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 2,549 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 1.82 higher (95% confidence interval 1.69-1.96); p = 3 × 10−131.
How common The G allele had a frequency of about 4% in the people studied.
Where it sits Chromosome 6, band 6p21.33 — in a non-coding transcript of HLA-B.
What each result means
A/ANo copy of the version the research linked to Transcription initiation factor IIA subunit 2 levels. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Transcription initiation factor IIA subunit 2 levels. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Transcription initiation factor IIA subunit 2 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs115881826 is a single position in the genome, in or near the HLA-B gene. Published research associates it with transcription initiation factor iia subunit 2 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does rs115881826 affect how medicines work?
HLA-B carries pharmacogenomic findings for Abacavir, Allopurinol, Carbamazepine and oxcarbazepine. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs115881826 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs115881826 come from?
GWAS Catalog, Nature genetics 2024, PMID:39528825. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 2711123316Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)3ByteDance (Doubao)3Others16Total27Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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