A/APublished research associates this genotype with typical/baseline likelihood of Acute anterior uveitis in ankylosing spondylitis — no copies of the reported risk allele.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Acute anterior uveitis in ankylosing spondylitis.
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Acute anterior uveitis in ankylosing spondylitis compared to the general population.
rs115879499 is a single position in the genome, in or near the HLA-B gene. Published research associates it with acute anterior uveitis in ankylosing spondylitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs115879499 linked to?
On MyGeneLog this position is linked to Ankylosing Spondylitis. The research behind each link, and its sources, are set out on that condition page.
Does rs115879499 affect how medicines work?
HLA-B carries pharmacogenomic findings for Abacavir, Allopurinol, Carbamazepine and oxcarbazepine. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs115879499 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs115879499 come from?
GWAS Catalog, Arthritis Rheumatol 2014, PMID:25200001. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.