alpha-2-macroglobulin receptor-associated protein levels
HLA-B · rs114811870
0 1612211Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others11Total16Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 2,935 Qatari ancestry individuals.
The effect
Each copy of the T allele shifted the measure 2.15 higher (95% confidence interval 1.96-2.35); p = 1 × 10−105.
How common The T allele had a frequency of about 2% in the people studied.
Where it sits Chromosome 6, band 6p21.33 — in the 5′ untranslated region of HLA-B.
What each result means
C/CNo copy of the version the research linked to alpha-2-macroglobulin receptor-associated protein levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to alpha-2-macroglobulin receptor-associated protein levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to alpha-2-macroglobulin receptor-associated protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Human molecular genetics · 2023 · PMID 36168886 · open access
Questions about rs114811870
What is rs114811870?
rs114811870 is a single position in the genome, in or near the HLA-B gene. Published research associates it with alpha-2-macroglobulin receptor-associated protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does rs114811870 affect how medicines work?
HLA-B carries pharmacogenomic findings for Abacavir, Allopurinol, Carbamazepine and oxcarbazepine. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs114811870 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs114811870 come from?
GWAS Catalog, Human molecular genetics 2023, PMID:36168886. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1612211Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others11Total16Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
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alpha-2-macroglobulin receptor-associated protein levels (rs114811870). MyGeneLog™. https://www.mygenelog.com/variants/rs114811870