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Who was studied 98,316 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.00402 lower (95% confidence interval 0.0034-0.0047); p = 2 × 10−33.
How common The G allele had a frequency of about 18% in the people studied.
Where it sits Chromosome 16, band 16q13 — in an intron of CETP.
What each result means
A/ANo copy of the version the research linked to Cholesterol in Small HDL. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Cholesterol in Small HDL. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Cholesterol in Small HDL. That is the strongest link of the three results. A link in a study is not a diagnosis.
Ophthalmology science · 2024 · PMID 39091897 · open access
Questions about rs11076175
What is rs11076175?
rs11076175 is a single position in the genome, in or near the CETP gene. Published research associates it with cholesterol in small hdl. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11076175 linked to?
On MyGeneLog this position is linked to Age-Related Macular Degeneration. The research behind each link, and its sources, are set out on that condition page.
Does rs11076175 affect how medicines work?
CETP carries pharmacogenomic findings for Statins. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs11076175 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11076175 come from?
GWAS Catalog, Ophthalmology science 2024, PMID:39091897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Cholesterol in Small HDL (rs11076175). MyGeneLog™. https://www.mygenelog.com/variants/rs11076175