Standard
HDL cholesterol
LPA · rs1084651
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of HDL cholesterol compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with HDL cholesterol.
G/G
Published research associates this genotype with typical/baseline likelihood of HDL cholesterol — no copies of the reported risk allele.
Source
Biological, clinical and population relevance of 95 loci for blood lipids
Teslovich TM,
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Koseki M,
Pirruccello JP,
Ripatti S,
Chasman DI,
Willer CJ,
Johansen CT,
Fouchier SW
and 197 more — show all
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Wilson JF,
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Wichmann HE,
Whitfield JB,
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Wareham NJ,
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Uitterlinden AG,
Uda M,
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Smit JH,
Sinisalo J,
Silander K,
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Scott J,
Schlessinger D,
Sanna S,
Salomaa V,
Saharinen J,
Sabatti C,
Ruokonen A,
Rudan I,
Rose LM,
Roberts R,
Rieder M,
Psaty BM,
Pramstaller PP,
Pichler I,
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Montgomery GW,
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McPherson R,
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Magnusson PK,
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Lettre G,
Langenberg C,
Launer LJ,
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Laaksonen R,
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Kronenberg F,
König IR,
Khaw KT,
Kaprio J,
Kaplan LM,
Johansson A,
Jarvelin MR,
Janssens AC,
Ingelsson E,
Igl W,
Kees Hovingh G,
Hottenga JJ,
Hofman A,
Hicks AA,
Hengstenberg C,
Heid IM,
Hayward C,
Havulinna AS,
Hastie ND,
Harris TB,
Haritunians T,
Hall AS,
Gyllensten U,
Guiducci C,
Groop LC,
Gonzalez E,
Gieger C,
Freimer NB,
Ferrucci L,
Erdmann J,
Elliott P,
Ejebe KG,
Döring A,
Dominiczak AF,
Demissie S,
Deloukas P,
de Geus EJ,
de Faire U,
Crawford G,
Collins FS,
Chen YD,
Caulfield MJ,
Campbell H,
Burtt NP,
Bonnycastle LL,
Boomsma DI,
Boekholdt SM,
Bergman RN,
Barroso I,
Bandinelli S,
Ballantyne CM,
Assimes TL,
Quertermous T,
Altshuler D,
Seielstad M,
Wong TY,
Tai ES,
Feranil AB,
Kuzawa CW,
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Nature · 2010 · PMID 20686565 · open access
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs1084651
What is rs1084651?
rs1084651 is a single position in the genome, in or near the LPA gene. Published research associates it with hdl cholesterol. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What do people read about alongside rs1084651?
Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (1 papers), cholesterol and blood fats (1 papers), heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs1084651 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1084651 come from?
GWAS Catalog, Nature 2010, PMID:20686565. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants