Standard

HDL cholesterol

LIPC · rs10468017

Where this position leads

Condition: Cholesterol (LDL, HDL and Total)

rs10468017 Condition: Cholesterol (LDL, HDL and Total) Cholesterol (LDL, HDL and Total) Condition Topic: Heart and circulation Heart and circulation Topic Topic: Short-sightedness and screens Short-sightedness and screens Topic rs10468017 rs10468017 LIPC

Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.

What the study found

Who was studied 19,840 European ancestry individuals; replicated in Up to 20,623 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.1 s.d. higher (95% confidence interval 0.06-0.14); p = 8 × 10−23.

How common The T allele had a frequency of about 30% in the people studied.

Where it sits Chromosome 15, band 15q21.3 — inside ALDH1A2.

What each result means

C/C No copy of the version the research linked to HDL cholesterol. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to HDL cholesterol. That is a smaller link than two copies.
T/T Two copies of the version the research linked to HDL cholesterol. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs10468017

What is rs10468017?

rs10468017 is a single position in the genome, in or near the LIPC gene. Published research associates it with hdl cholesterol. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10468017 linked to?

On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs10468017?

Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (3 papers), short-sightedness and screens (3 papers), blood sugar and insulin (1 papers), cholesterol and blood fats (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs10468017 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10468017 come from?

GWAS Catalog, Nat Genet 2008, PMID:19060906. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

HDL cholesterol (rs10468017). MyGeneLog™. https://www.mygenelog.com/variants/rs10468017

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