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NEDD4L

NEDD4L is a gene. This site has 18 published variants inside it and 3 near it, each from a published genetic study, joining it to 5 condition pages.

What prescribing experts say about NEDD4L (1)

CPIC, the international group that writes gene-based prescribing guidelines, rates how strong the evidence is for each gene and medicine, from A (strong enough to change the prescription) to D (weak or conflicting). Every rating is shown, the weak ones included, so you can see where the evidence stops.

• hydrochlorothiazide · level D: weak or conflicting (provisional)

Source: CPIC (Clinical Pharmacogenetics Implementation Consortium), public domain (CC0), copy kept on this site and refreshed weekly.

Conditions it is linked to

• Age-Related Macular Degeneration
• Celiac Disease
• Educational Attainment
• Height
• Obesity and Body Weight

Variants inside NEDD4L (18)

• rs7243073 · Aspartate aminotransferase levels
• rs4940668 · Educational attainment
• rs62096389 · Gamma glutamyl transferase levels
• rs6566953 · Gamma glutamyl transferase levels
• rs572657149 · GLIPR1 protein levels
• rs4941333 · Height
• rs9675944 · Highest math class taken
• rs4940386 · Highest math class taken (MTAG)
• rs7230600 · Left ventricular end-systolic volume
• rs7233294 · NTPROBNP protein levels
• rs2046707868 · Periventricular nodular heterotopia 7
• rs2059194330 · Periventricular nodular heterotopia 7
• rs2059723813 · Periventricular nodular heterotopia 7
• rs2516772394 · Periventricular nodular heterotopia 7
• rs879255597 · Periventricular nodular heterotopia with syndactyly, cleft palate and developmental delay
• rs879255598 · Periventricular nodular heterotopia with syndactyly, cleft palate and developmental delay
• rs879255599 · Periventricular nodular heterotopia with syndactyly, cleft palate and developmental delay
• rs17808190 · Self-reported math ability

Variants near NEDD4L (3)

Positions outside the gene, filed under it because it is the closest. A variant near a gene does not always act through it.

• rs114509377 · Free Cholesterol to Cholesteryl Esters in Small HDL ratio
• rs12373325 · Gamma glutamyl transferase levels
• rs143393480 · Weight

See NEDD4L with everything it connects to on the Gene Knowledge Graph, or as data at /api/v1/genes/NEDD4L.

A gene page gathers published research; it is not a test result and not medical advice. If a gene matters to your health, talk to a doctor or a genetic counsellor.