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Gene

GRK5

GRK5 is a gene. This site has 5 published variants inside it and 7 near it, each from a published genetic study, joining it to 5 condition pages.

What prescribing experts say about GRK5 (13)

CPIC, the international group that writes gene-based prescribing guidelines, rates how strong the evidence is for each gene and medicine, from A (strong enough to change the prescription) to D (weak or conflicting). Every rating is shown, the weak ones included, so you can see where the evidence stops.

• acebutolol · level C: not enough to change the prescription
• atenolol · level C: not enough to change the prescription
• betaxolol · level C: not enough to change the prescription
• bisoprolol · level C: not enough to change the prescription
• carvedilol · level C: not enough to change the prescription
• esmolol · level C: not enough to change the prescription
• labetalol · level C: not enough to change the prescription
• metoprolol · level C: not enough to change the prescription
• nadolol · level C: not enough to change the prescription
• nebivolol · level C: not enough to change the prescription
• pindolol · level C: not enough to change the prescription
• propranolol · level C: not enough to change the prescription
• sotalol · level C: not enough to change the prescription

Source: CPIC (Clinical Pharmacogenetics Implementation Consortium), public domain (CC0), copy kept on this site and refreshed weekly.

Conditions it is linked to

• Alzheimer's Disease
• Blood Cell Counts
• Celiac Disease
• Height
• Type 2 Diabetes

Variants inside GRK5 (5)

• rs61876100 · Glycoprotein acetyls (mainly a1-acid glycoprotein) meal response (LMM)
• rs10787955 · Height (baseline)
• rs61876596 · Height (baseline)
• rs10886430 · Mean platelet volume
• rs10886471 · Type 2 diabetes

Variants near GRK5 (7)

Positions outside the gene, filed under it because it is the closest. A variant near a gene does not always act through it.

• rs1368039384 · Alzheimer's disease or family history of Alzheimer's disease
• rs771041661 · Alzheimer's disease or family history of Alzheimer's disease
• rs11198820 · Body shape phenotype PC2
• rs11198821 · Body shape phenotype PC3
• rs7923896 · Height (baseline)
• rs61876592 · Physical function (baseline)
• rs7358070 · PRDX3 protein levels

See GRK5 with everything it connects to on the Gene Knowledge Graph, or as data at /api/v1/genes/GRK5.

A gene page gathers published research; it is not a test result and not medical advice. If a gene matters to your health, talk to a doctor or a genetic counsellor.