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Gene

BRCA2

BRCA2 DNA repair associated

BRCA2, like BRCA1, helps repair broken DNA. Rare harmful changes in it raise the risk of breast, ovarian and some other cancers, and are found by clinical genetic testing. The common variants on this page are not those rare changes.

Conditions it is linked to

Variants inside BRCA2 (9)

Questions about BRCA2

What is the difference between BRCA1 and BRCA2?

Both help repair DNA, and harmful changes in either raise cancer risk. They are different genes, and the cancers they are most linked to differ somewhat.

Are the BRCA2 variants on this page the risky ones?

No. The common variants here shift risk only a little; the high-risk BRCA2 changes are rare and found by clinical testing.

See BRCA2 with everything it connects to on the Gene Knowledge Graph, or as data at /api/v1/genes/BRCA2.

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BRCA2 gene. MyGeneLog™. https://www.mygenelog.com/genes/BRCA2

A gene page gathers published research; it is not a test result and not medical advice. If a gene matters to your health, talk to a doctor or a genetic counsellor.