Allergic Conjunctivitis, as genome-wide studies have reported it: 3 positions from 1 study, the largest recording 45,734 cases and 1,084,159 controls (European ancestry). Built from the GWAS Catalog's records and rebuilt when a new position is reported; the figures are the studies'.
This is the record of what genome-wide association studies have found for Allergic Conjunctivitis (the GWAS Catalog's "Allergic conjunctivitis"): 3 positions reported by 1 study. The page is put together by code from the catalogue's records and the studies' own listings, and it is rebuilt whenever the records change, so it always reflects them as they stand.
Koskimäki F et al. 2026, in The Journal of Allergy and Clinical Immunology — Characterization of genetic loci associated with allergic conjunctivitis. Studied in 45,734 cases and 1,084,159 controls (European ancestry). From it, 3 positions on this page: rs2508569 (near COX7CP3), rs9923856 (CLEC16A), rs6691738 (TNFSF4). PMID:41482248.
The 3 positions lie in or near 3 genes: COX7CP3, CLEC16A, TNFSF4. A gene named here is the catalogue's mapped location for a position, not a mechanism; the studies are cited above so that a reader can go to them.
The strongest association in the records is rs2508569 near COX7CP3, reported by Koskimäki F et al. 2026 at P = 2 × 10-15, with an odds ratio of 1.06.
Read this page as a list of findings about Allergic Conjunctivitis, not as an account of it. Each finding is a position that a genome-wide study linked to the condition across a population; the page adds no description, no prevalence and no advice, because the records hold none. The variant pages linked above give each study's record for its position, and ClinVar's where one exists.
Nothing on this page diagnoses Allergic Conjunctivitis. The 3 variants here are research findings; no guideline uses them to predict, screen for or diagnose the condition — that is a clinician's work.
This page was assembled by code from association records. It holds no clinical guidance, because its sources hold none: a genome-wide study reports which positions differ between people with a condition and people without, at the population level, and that is all this page repeats. A question about a symptom, a test or a treatment belongs with a clinician.
What a 23andMe/AncestryDNA export or raw VCF can and can't tell you about Allergic Conjunctivitis comes down to these specific, well-studied positions — not a diagnosis.
Databases, guidelines and references
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Allergic Conjunctivitis. MyGeneLog™. https://www.mygenelog.com/conditions/allergic-conjunctivitis
In the GWAS Catalog, Allergic Conjunctivitis is filed as "Allergic conjunctivitis". Rather than define it, this page lists the genome-wide findings: 3 positions from 1 study, each with its study's sample and citation.
Genes play a part: 3 positions have been linked to it, the largest study recording 45,734 cases and 1,084,159 controls (European ancestry). But each is a common variant of small effect, and a link found across a population does not cause the condition in any one person.
The positions lie in or near 3 genes: COX7CP3, CLEC16A, TNFSF4. A mapped gene is the catalogue's location for a position, not a mechanism.
No. They are population-level findings of small effect. Allergic Conjunctivitis is diagnosed by a clinician, and no guideline uses a genotype to predict it.
Free to reuse. This page's text is original writing from freely-available research, licensed CC BY 4.0 — reuse it, including commercially, with attribution to MyGeneLog™. It's general research-derived information, not medical advice or a diagnosis — see Terms of Use.