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Who was studied 45,734 European ancestry cases, 1,084,159 European ancestry controls.
The effect
Each copy of the G allele carried 1.06 times the odds of Allergic conjunctivitis (95% confidence interval 1.05-1.08); p = 2 × 10−15.
How common The G allele had a frequency of about 69% in the people studied.
Where it sits Chromosome 11, band 11q23.3 — between genes, 12.6 kb from COX7CP3.
What each result means
C/CNo copy of the version the research linked to Allergic conjunctivitis. This is the starting point the study compared everyone against.
C/GOne copy of the version the research linked to Allergic conjunctivitis. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Allergic conjunctivitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
The Journal of allergy and clinical immunology · 2026 · PMID 41482248
Questions about rs2508569
What is rs2508569?
rs2508569 is a single position in the genome, in or near the near COX7CP3 gene. Published research associates it with allergic conjunctivitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2508569 linked to?
On MyGeneLog this position is linked to Allergic Conjunctivitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs2508569 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2508569 come from?
GWAS Catalog, The Journal of allergy and clinical immunology 2026, PMID:41482248. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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