Sensitive

Type 2 diabetes

RAMP2-AS1 · rs9892728

Where this position leads

Condition: Type 2 Diabetes

rs9892728 Condition: Type 2 Diabetes Type 2 Diabetes Condition rs9892728 rs9892728 RAMP2-AS1

What the study found

Who was studied 46,511 Asian ancestry cases, 169,776 Asian ancestry controls.

The effect Each copy of the C allele shifted the measure 0.0536 higher (95% confidence interval 0.035-0.072); p = 9 × 10−9.

How common The C allele had a frequency of about 47% in the people studied.

Where it sits Chromosome 17, band 17q21.2 — a synonymous change in RAMP2-AS1.

What each result means

C/C Two copies of the version the research linked to Type 2 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Type 2 diabetes. That is a smaller link than two copies.
T/T No copy of the version the research linked to Type 2 diabetes. This is the starting point the study compared everyone against.
Source

Questions about rs9892728

What is rs9892728?

rs9892728 is a single position in the genome, in or near the RAMP2-AS1 gene. Published research associates it with type 2 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9892728 linked to?

On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.

Does having rs9892728 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9892728 come from?

GWAS Catalog, Nature genetics 2020, PMID:32541925. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Type 2 diabetes (rs9892728). MyGeneLog™. https://www.mygenelog.com/variants/rs9892728

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