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Who was studied 286 African American or Afro-Caribbean cases, 121,446 African American or Afro-Caribbean controls, 19,217 European ancestry cases, 419,674 European ancestry controls, 429 Hispanic or Latin American cases, 59,212 Hispanic or Latin American controls.
The effect
Each copy of the G allele shifted the measure 0.0781 higher (95% confidence interval 0.055-0.101); p = 1 × 10−12.
How common The G allele had a frequency of about 52% in the people studied.
Where it sits Chromosome 3, band 3q28 — between genes, 149.1 kb from TP63.
What each result means
A/ANo copy of the version the research linked to Squamous cell carcinoma (PheCode 172.22). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Squamous cell carcinoma (PheCode 172.22). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Squamous cell carcinoma (PheCode 172.22). That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs9834622
What is rs9834622?
rs9834622 is a single position in the genome, in or near the near TP63 gene. Published research associates it with squamous cell carcinoma (phecode 172.22). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs9834622 linked to?
On MyGeneLog this position is linked to Squamous Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs9834622 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9834622 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1114123Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI4Microsoft · Copilot1Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others3Total11Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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