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Who was studied 276 African American or Afro-Caribbean cases, 121,333 African American or Afro-Caribbean controls, 769 European ancestry cases, 449,707 European ancestry controls.
The effect
Each copy of the A allele shifted the measure 2.66 lower (95% confidence interval 2.62-2.69); p = 2 × 10−11.
How common The A allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 12, band 12q12 — between genes, 94.2 kb from LINC02450.
What each result means
A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Acute pericarditis (PheCode 420.21) compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Acute pericarditis (PheCode 420.21).
G/GPublished research associates this genotype with typical/baseline likelihood of Acute pericarditis (PheCode 420.21) — no copies of the reported risk allele.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs966455665
What is rs966455665?
rs966455665 is a single position in the genome, in or near the near LINC02450 gene. Published research associates it with acute pericarditis (phecode 420.21). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs966455665 linked to?
On MyGeneLog this position is linked to Acute Pericarditis. The research behind each link, and its sources, are set out on that condition page.
Does having rs966455665 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs966455665 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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